Human Jagged-1 Recombinant Protein Fc Tag from Innovative Research has been recombinantly produced in HEK293 cells. This is a Liquid protein buffered in 0.2um-filtered solution in PBS. with a purity of >90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ and#956;g purified protein (LAL test; Lonza)..

More Details:

• Species: Human
• Target: JAG1
• Purity: >90% (SDS-PAGE).
  
  Endotoxin level is less than 0.1EU/ and#956;g purified protein (LAL test; Lonza).
• Source: HEK293 cells
• Storage Conditions: Working aliquots are stable for up to 3 months when stored at -20°C.

Additional Information:

Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late sTages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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