Human IL-1R9 Recombinant Protein C-Fc Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 Cells. The protein formulation is lyophilized from sterile 100mM Glycine; 10mM NaCl; 50mM Tris; pH 7.5 with a purity of > 95 % as determined by reducing SDS-PAGE..

More Details:

• Species: Human
• Target: IL-1R9
• Purity: > 95 % as determined by reducing SDS-PAGE..< 1.0 EU per ug as determined by the LAL method.
• Source: HEK293 Cells
• Storage Conditions: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.

X-linked interleukin-1 receptor accessory protein-like 2 (IL1RAPL2) or Interleukin-1 receptor 9 (IL-1R9) is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins. IL-1R9/IL1RAPL2 shows restricted expression in fetal brain and is highly homologous to IL1RAPL; which is reportedly involved in nonsyndromic X-linked mental retardation. IL-1R9/IL1RAPL2 is highly homologous to IL-1R8. Both forms have no known ligands and receptor are found in the fetal brain. IL-1R9/IL1RAPL2 may function as a negative receptor. Both IL1RAPL1 and IL1RAPL2 have novel C-terminal sequences not present in other related proteins. IL-1R9/IL1RAPL2 may be strong candidates for X-linked non-syndromic mental retardation loci; and that molecules resembling IL-1 and IL-18 play a role in the development or function of the central nervous system.

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