Human GFRRA2 Recombinant Protein C-Fc-6His Tag Lyophilized

Human GFRRA2 Recombinant Protein C-Fc-6His Tag Lyophilized from Innovative Research has been recombinantly produced in Human Cells. The protein formulation is lyophilized from a 0.2 ?m filtered solution of 20mM Tris,150mM NaCl,pH8.0. with a purity of > 95 % as determined by reducing SDS-PAGE..

More Details:

• Species: Human
• Target: GFRRA2
• Purity: > 95 % as determined by reducing SDS-PAGE..< 1.0 EU per ug as determined by the LAL method.
• Source: Human Cells
• Storage Conditions: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.

GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. GFRA2 mediates the NRTN-induced autophosphorylation and activation of the RET receptor. It also able to mediate GDNF signaling through the RET tyrosine kinase receptor. It acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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