Human GCN5 highly active Recombinant Protein His Tag

Human GCN5 highly active Recombinant Protein His Tag from Innovative Research has been recombinantly produced in Sf21 cells. This is a Liquid protein buffered in In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. with a purity of >95% (SDS-PAGE).

More Details:

• Species: Human
• Target: KAT2A
• Purity: >95% (SDS-PAGE)
• Source: Sf21 cells
• Storage Conditions: Stable for at least 6 months after receipt when stored at -80°C.

Additional Information:

GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific Tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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