Human Factor II (Prothrombin) PurifiedIHUFII9MG
Human Factor II (Prothrombin) Purified from Innovative Research has been purified from human plasma. This is a frozen liquid buffered in 20 mM Tris-HCl/0.1 M NaCl/pH 7.4, with a concentration of 9mg/ml and a purity of greater than 95% as determined by SDS-PAGE analysis (showing no reduction when incubated with 2-mercaptoethanol).
Prothrombin (Coagulation Factor II) is converted to active Thrombin (FIIa) during the coagulation cascade. This happens when Factor Xa and its cofactor, Factor V, together cleave Prothrombin in two, creating a fragment (fragment 1.2, which is formed from the N-terminal Gla domain and two Kringle domains of Prothrombin) and thrombin (containing only the serine protease domain).
- Source: Human Plasma
- Purity: >95% by SDS-PAGE
- Storage Conditions: -60° to -80°C
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Please note – this product replaces our old product number IHPT (same product, new number).
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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