*Human Factor II (Prothrombin) Purified

Select this product for Molecular Innovations name, Human Prothrombin and product number, HFII. Human Factor II (Prothrombin) Purified from Innovative Research has been purified from human plasma. This is a frozen liquid buffered in 20 mM Tris-HCl/0.1 M NaCl/pH 7.4, and a purity of greater than 95% as determined by SDS-PAGE analysis (showing no reduction when incubated with 2-mercaptoethanol). Prothrombin (Coagulation Factor II) is converted to active Thrombin (FIIa) during the coagulation cascade. This happens when Factor Xa and its cofactor, Factor V, together cleave Prothrombin in two, creating a fragment (fragment 1.2, which is formed from the N-terminal Gla domain and two Kringle domains of Prothrombin) and thrombin (containing only the serine protease domain). More Details: Source: Human Plasma Purity: >95% by SDS-PAGE Storage Conditions: -60░ to -80░C At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results. Please note ŌĆō this product replaces our old product number IHPT (same product, new number).