*Human Factor II (Prothrombin) Purified
IHUFII9MGSelect this product for Molecular Innovations name, Human Prothrombin and product number, HFII.
Human Factor II (Prothrombin) Purified from Innovative Research has been purified from human plasma. This is a frozen liquid buffered in 20 mM Tris-HCl/0.1 M NaCl/pH 7.4, with a concentration of 9mg/ml and a purity of greater than 95% as determined by SDS-PAGE analysis (showing no reduction when incubated with 2-mercaptoethanol).
Prothrombin (Coagulation Factor II) is converted to active Thrombin (FIIa) during the coagulation cascade. This happens when Factor Xa and its cofactor, Factor V, together cleave Prothrombin in two, creating a fragment (fragment 1.2, which is formed from the N-terminal Gla domain and two Kringle domains of Prothrombin) and thrombin (containing only the serine protease domain).
More Details:
- Source: Human Plasma
- Purity: >95% by SDS-PAGE
- Storage Conditions: -60° to -80°C
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Please note – this product replaces our old product number IHPT (same product, new number).
These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.
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