Human Factor Alpha XIIa PurifiedIHUFXIIAA500UG
Human Factor Alpha XIIa Purified from Innovative Research has been prepared from Human Factor XII using Dextran Sulfate, and then purified to remove the activator. This is a frozen liquid buffered in 4 mM sodium acetate-HCl/ 0.15 M NaCl/ pH 5.3, with a concentration of 1mg/ml. Complete activation was observed by SDS-PAGE analysis.
Factor alpha-XIIa activates Factor XI to FXIa as part of the contact activation pathway in the coagulation cascade. Factor XIIa activates prekallikrein to kallikrein, which in turn converts FXII to FXIIa in a reciprocal activation mechanism that triggers the contact factor cascade.
- Source: Human Plasma
- Purification: Prepared from Human Factor XII using Dextran Sulfate (which was then removed by purification)
- Purity: Complete activation observed on SDS-PAGE
- Storage Conditions: -60° to -80°C
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Please note – this product replaces our old product number IHFXIIa (same product, new number).
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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