Human Factor Alpha XIIa Purified
IHUFXIIAA500UGHuman Factor Alpha XIIa Purified from Innovative Research has been prepared from Human Factor XII using Dextran Sulfate, and then purified to remove the activator. This is a frozen liquid buffered in 4 mM sodium acetate-HCl/ 0.15 M NaCl/ pH 5.3, with a concentration of 1mg/ml. Complete activation was observed by SDS-PAGE analysis.
Factor alpha-XIIa activates Factor XI to FXIa as part of the contact activation pathway in the coagulation cascade. Factor XIIa activates prekallikrein to kallikrein, which in turn converts FXII to FXIIa in a reciprocal activation mechanism that triggers the contact factor cascade.
More Details:
- Source: Human Plasma
- Purification: Prepared from Human Factor XII using Dextran Sulfate (which was then removed by purification)
- Purity: Complete activation observed on SDS-PAGE
- Storage Conditions: -60° to -80°C
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
Please note – this product replaces our old product number IHFXIIa (same product, new number).
These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.
Please be aware the image pictured is for illustrative purposes only, and your product packaging and appearance may vary.
Get in touch with our team! Please include any relevant information (product name, etc)
