Human Carboxypeptidase E Recombinant Protein C-6His Tag

Human Carboxypeptidase E Recombinant Protein C-6His Tag from Innovative Research has been recombinantly produced in Human Cells. The protein formulation is supplied as a 0.2 ?m filtered solution of 20mM TrisHCl,150mM NaCl,1mM ZnCl2,10%Glycerol,pH7.5. with a purity of > 95 % as determined by reducing SDS-PAGE..

More Details:

• Species: Human
• Target: Carboxypeptidase E
• Purity: > 95 % as determined by reducing SDS-PAGE..< 1.0 EU per ug as determined by the LAL method.
• Source: Human Cells
• Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

The active form of CPE cleaves C-terminal amino acid residues of the peptide, and is thus involved in the biosynthesis of peptide hormones and neurotransmitters including insulin, enkephalin, etc. It is thought that membrane-associated CPE acts as a sorting receptor for targeting regulated secretory proteins which are mostly prohormones and neuropeptides in the trans-Golgi network of the pituitary and in secretory granules into the secretory pathway. Defects in this protein are implicated in type II diabetes due to impaired glucose clearance and insulin resistance.

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For research use only.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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