Human Apolipoprotein AI Recombinant Protein C-His Tag Lyophilized

Human Apolipoprotein AI Recombinant Protein C-His Tag Lyophilized from Innovative Research has been recombinantly produced in Human Cells. The protein formulation is lyophilized from a 0.2 ?m filtered solution of 20mM PB; 150mM NaCl; pH 7.2. with a purity of > 95% as determined by reducing SDS-PAGE..

More Details:

• Species: Human
• Target: Apolipoprotein AI
• Purity: > 95% as determined by reducing SDS-PAGE..< 1.0 EU per ?g as determined by the LAL method.
• Source: Human Cells
• Storage Conditions: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.

Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes; such as Cholesterol metabolism; Lipid metabolism and transport; Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies; including Tangier disease (TGD); systemic non-neuropathic amyloidosis; premature coronary artery disease; hepatosplenomegaly and progressive muscle wasting and weakness. In addition; ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.

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For research use only.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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