Fungus-Derived Ribonuclease T1 Animal Free PurifiedIFGRNASET1AF100KU
Fungus-Derived Ribonuclease T1 Animal Free Purified from Innovative Research has been prepared as a highly purified, microbial (non-mammalian) RNase prepared with non-animal components. This has a concentration of 300,000 units/mg protein.
This product is a non-mammalian endoribonuclease, specifically for the cleavage of RNA (deaminated RNA) between guanosine 3’-phosphate residues (or inosine 3’-phosphate) and the 5’-OH residues of adjacent nucleotides with the formation of the corresponding intermediate 2’, 3’-cyclic phosphates. It cleaves single-stranded RNA releasing oligonucleotides from the guanosine 3’-phosphate termini. This product has multiple applications in molecular cloning and DNA sequencing. RNase T1 is inhibited by Ag+, Zn2+, Cu2+, and Hg2+ at 1 X mM. The stimulatory effects of both histidine and EDTA are attributed to chelation of contaminating inhibitor cations.
- Source: Fungus (Aspergillus oryzae)
- Purification: chromatographically purified
- Storage Conditions: 2-8°C
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These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.
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