Bacteria-Derived TDO Anopheles gambiae Recombinant Protein His Tag

Bacteria-Derived TDO Anopheles gambiae Recombinant Protein His Tag from Innovative Research has been recombinantly produced in E. coli. This is a Liquid protein buffered in In 50mM sodium phosphate pH 8.0, containing 0.15M sodium chloride, 0.2M imidazole and 10% glycerol. with a purity of >98% (SDS-PAGE).

More Details:

• Species: Bacteria-Derived
• Target: T23O_ANOGA
• Purity: >98% (SDS-PAGE)
• Source: E. coli
• Storage Conditions: Stable for at least 6 months after receipt when stored at -80°C.

Additional Information:

Tryptophan 2,3-dioxygenase (TDO) is a heme-containing dioxygenase catalyzing the addition of molecular oxygen across the 2,3-double bond of the indole ring of tryptophan to form N-formylkynurenine (NFK). In Anopheles gambiae, TDO is the only enzyme able to catalyze the first and rate-limiting step in L-Trp catabolism through the kynurenine pathway. Tryptophan is an essential amino acid for protein synthesis and also the precursor for production of a number of neurotransmitters, such as serotonin and melatonin; in mosquitoes, the kynurenine pathway is essential for eye pigmentation. Conceivably, the tryptophan-using pathways should be regulated in a coordinated manner in mosquitoes as well as in other species and TDO activation/inactivation processes could play an essential role in these phenomena.

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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