Bacteria-Derived MAP1LC3B Recombinant Protein Lyophilized

Bacteria-Derived MAP1LC3B Recombinant Protein Lyophilized from Innovative Research has been recombinantly produced in E.coli. The protein formulation is lyophilized from a 0.2 ?m filtered solution of 20mM Tris, 150mM NaCl, 2mM DTT, pH8.0. with a purity of > 95% as determined by reducing SDS-PAGE..

More Details:

• Species: Human
• Target: MAP1LC3B
• Purity: > 95% as determined by reducing SDS-PAGE..< 1.0 EU per ?g as determined by the LAL method.
• Source: E.coli
• Storage Conditions: Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at < -20? for 3 months.

Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include MAP1LC3A, MAP1LC3C, and MAP1LC3B2). It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LMAP1LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. MAP1LC3B also plays a role in autophagy, a process that involves the bulk degradation of cytoplasmic component.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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