Bacteria-Derived Creatine Kinase BB Recombinant Protein N-His Tag

Bacteria-Derived Creatine Kinase BB Recombinant Protein N-His Tag from Innovative Research has been recombinantly produced in E.coli. The protein formulation is supplied as a 0.2 ?m filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH 7.5. with a purity of > 90% as determined by reducing SDS-PAGE..

More Details:

• Species: Human
• Target: Creatine Kinase BB
• Purity: > 90% as determined by reducing SDS-PAGE..< 1.0 EU per ?g as determined by the LAL method.
• Source: E.coli
• Storage Conditions: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Creatine kinase B-type (CKB) belongs to the ATP:guanido phosphotransferase family. It has dimer of identical or non-identical chains with MM being the major form in skeletal muscle and myocardium. MB exists in myocardium, and BB exists in many tissues, especially brain. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Clinically, creatine kinase is assayed in blood tests as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, autoimmune myositides and acute renal failure.

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For research use only.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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