Bacteria-Derived Clusterin nuclear form Recombinant Protein His Tag

Bacteria-Derived Clusterin nuclear form Recombinant Protein His Tag from Innovative Research has been recombinantly produced in E. coli. This is a Liquid protein buffered in 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. with a purity of >90% (SDS-PAGE).

Endotoxin level is less than 1EU/ and#956;g purified protein (LAL test; Lonza)..

More Details:

• Species: Bacteria-Derived
• Target: CLU
• Purity: >90% (SDS-PAGE).
  
  Endotoxin level is less than 1EU/ and#956;g purified protein (LAL test; Lonza).
• Source: E. coli
• Storage Conditions: Working aliquots are stable for up to 3 months when stored at -20°C.

Additional Information:

Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.

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This material is sold for in-vitro use only for research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herein are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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