Factor IX Genetically Deficient (Knockout) Products are applicable to a wide range of in vitro research applications (including ELISA and Western Blot) andformany different areas of research, including coagulation and fibrinolysis. Factor IX deficiency is an animal model for Hemophilia B (Christmas Disease).
Our Factor IX Knockout was created by targeted disruption of the F9 gene. Mutations were then confirmed by PCR genotyping, Sanger sequencing, and RT-PCR. These Knockout animal models experience prolonged clotting time (aPTT) and mortality upon tail clipping without cauterization.
Products available include genetically deficient plasma, organs (flash-frozen), lyophilized organ powders, and ready-to-use organ tissue lysates. These products are ideal for use as standards or controls, including use as a negative control.
We also offer Knockout Mice, available as individual male and/or female mice as well as breeding pairs. These Research Models are fully licensed and maintained as live colonies with immediate availability.Contact us directlyfor more information about live Research Models.