C1 Inhibitor Deficient Products

C1 Inhibitor Genetically Deficient (Knockout) Products are applicable to a wide range of in vitro research applications (including ELISA and Western Blot) and for many different areas of research, including hemorrhagic shock, septic shock, transplant rejection, reperfusion injury, inflammatory disorders, and hereditary angioedema. 

Our off-the-shelf C1 Inhibitor Knockout Mouse products are available from Homozygous Knockout Mice. Our C1 Inhibitor Homozygous Knockout was created by targeted excision of the SERPING1 gene, and these mice completely lack C1 Inhibitor protein expression. 

Products available include genetically deficient plasma, organs (flash-frozen), lyophilized organ powders, and ready-to-use organ tissue lysates. These products are ideal for use as standards or controls, including use as a negative control. 

Additionally, we offer Knockout Mice in individual male and/or female mice as well as breeding pairs. Our C1 Inhibitor Knockout models are available in homozygous form, as well as heterozygous mice that function as an animal model of human Hereditary Angioedema (HAE). These Research Models are fully licensed and maintained as live colonies with immediate availability. Contact us directly for more information about live Research Models.