Product References

Rapid Detection of an Ebola Biomarker with Optical Microring Resonators

Posted by Adam Awdish on

Rapid Detection of an Ebola Biomarker with Optical Microring Resonators

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Rapid Detection of an Ebola Biomarker with Optical Microring Resonators Abraham J. Qavi, Krista Meserve, M. Javad Aman, Hong Vu, Larry Zeitlin, John M. Dye, Jeffrey W. Froude, Daisy W. Leung, Lan Yang, Frederick W. Holtsberg,, Ryan C. Bailey, and Gaya K. Amarasinghe Cell Reports June 20, 2022 RNA viruses are particularly effective at causing diseases in human populations, partially because of their ability to rapidly mutate. One of the deadliest types of RNA viruses, Filoviruses, are single-stranded, negative-sense RNA viruses; an example of...

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Plasminogen and Plasmin can Bind to Human T Cells and Generate Truncated CCL21 that Increases Dendritic Cell Chemotactic Responses

Posted by Adam Awdish on

Plasminogen and Plasmin can Bind to Human T Cells and Generate Truncated CCL21 that Increases Dendritic Cell Chemotactic Responses

Human Alpha 2 Antiplasmin Purified Lyophilized from Innovative Research was used in the following study:   Plasminogen and Plasmin can Bind to Human T Cells and Generate Truncated CCL21 that Increases Dendritic Cell Chemotactic Responses Evert J. Loef, Hilary M. Sheppard, Nigel P. Birch, Rod Dunbar Journal of Biological Chemistry June 9, 2022 Plasmin, a broad-spectrum protease that is highly regulated, is formed from plasminogen. This normally occurs in the blood, as plasminogen is found in high concentrations in circulation where it’s converted to plasmin by plasminogen activators. There are also high levels of α2-antiplasmin in circulation, which is a...

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Characterization of Congenital Factor XII Deficiency in Taiwanese Patients: Identification of One Novel and One Common Mutation

Posted by Adam Awdish on

Characterization of Congenital Factor XII Deficiency in Taiwanese Patients: Identification of One Novel and One Common Mutation

Human Total Factor XII ELISA Kit from Innovative Research was used in the following study:   Characterization of Congenital Factor XII Deficiency in Taiwanese Patients: Identification of One Novel and One Common Mutation Sheng-Chieh Chou, Ching-Yeh Lin, Hsuan-Yu Lin, Chen-Hsueh Pai, Cheng-Ye Yu, Su-Feng Kuo, Jen-Shiou Lin, Po-Te Lin, Mei-Hua Hung, Han-Ni Hsieh, Hsiang-Chun Liu & Ming-Ching Shen International Journal of Hematology June 8, 2022 Factor XII (FXII) deficiency is a condition that results in prolonged activation time of thromboplastin without being linked to excessive bleeding, and roughly 2% of otherwise healthy blood donors are reported to be deficient in...

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Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation

Posted by Adam Awdish on

Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation

Mouse Non Swiss Albino Serum from Innovative Research was used in the following study:   Pre-Clinical In-Vitro Studies on Parameters Governing Immune Complex Formation Marie Fichter, Gesa Richter, Alexander Bepperling, and Paul Wassmann Pharmaceutics June 13, 2022 Biotherapeutics provide an opportunity to make huge advancements in medical treatments, however, their development is often challenged by undesirable or unexpected immunogenic events that present themselves in patients. This is characterized by the formation of anti-drug antibodies (ADAs), which, under certain conditions, may cause the formation of immune complexes (ICs) that can trigger cascades with effects on various cell types. Unfortunately, the connection...

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Low-Dose Self-Amplifying mRNA COVID-19 Vaccine Drives Strong Protective Immunity in Non-Human Primates Against SARS-CoV-2 Infection

Posted by Adam Awdish on

Low-Dose Self-Amplifying mRNA COVID-19 Vaccine Drives Strong Protective Immunity in Non-Human Primates Against SARS-CoV-2 Infection

Innovative Grade US Origin Monkey Rhesus Serum and Innovative Grade US Origin Mouse Balb C Serum from Innovative Research were used in the following study:   Low-Dose Self-Amplifying mRNA COVID-19 Vaccine Drives Strong Protective Immunity in Non-Human Primates Against SARS-CoV-2 Infection Amy R. Rappaport, Sue-Jean Hong, Ciaran D. Scallan, Leonid Gitlin, Arvin Akoopie, Gregory R. Boucher, Milana Egorova, J. Aaron Espinosa, Mario Fidanza, Melissa A. Kachura, Annie Shen, Gloria Sivko, Anne Van Abbema, Robert L. Veres & Karin Jooss Nature Communications June 7, 2022 As COVID-19 continues to be a global problem, people that were previously vaccinated or infected are getting...

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