Product References

Cynomolgus Monkey Products from Innovative Research

Posted by Wendy Wise on

Cynomolgus Monkey Products from Innovative Research

Innovative Research offers several cynomolgus monkey products for your research needs, including serum, albumin, and ELISA kits. Cynomolgus monkeys are ideal candidates for use in biological products because of their 90-93% genetic similarity to and recent evolutionary divergence from humans. Our Cynomolgus products support basic research in cardiology, toxicology, pathology, and immunology. Some of our most popular cynomolgus products are listed below.   Innovative Grade US Origin Monkey Cynomolgus Serum Innovative Grade US Origin Monkey Cynomolgus Serum from Innovative Research is manufactured using whole blood collections from type Cynomolgus monkeys. The animals used for this material are of US Origin, ensuring...

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TPA KO And PAI-1-KO Mouse Models

Posted by Wendy Wise on

TPA KO And PAI-1-KO Mouse Models

Innovative Research raises and supplies a variety of mouse models to use in research associated with Alzheimer’s Disease, obesity, stroke and brain damage, and aging. Of particular interest to these areas are our tPA KO and PAI-1-KO Mouse Models. Below we have selected a few scholarly findings to aid in your understanding of the research possibilities when using our mice to investigate illness and disease.  Explore Our Products >>>   Aging The aim of this study is to investigate age-dependent decline of endogenous tPA and the effects of tPA decline on glymphatic function and cognitive outcome in mice.  Deficiency of...

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Study examines miRNA biomarkers for ALS using plasma from Innovative Research

Posted by Wendy Wise on

Study examines miRNA biomarkers for ALS using plasma from Innovative Research

A study examines miRNA biomarkers for ALS using plasma from Innovative Research. The study was published in the Journal of The Neurological Sciences last month. Scientists examined miRNA biomarkers for ALS extracted from extracellular vesicles in blood samples using a large and diverse patient and control population. They determined that different blood collection and storage protocols by different investigators could impact repeatability of miRNA analysis. One hundred blinded, blood plasma samples were analyzed. Thirty-five men and 15 women with ALS were compared with controls consisting of 30 men and 20 women. None of the ALS patient cohort reported family members...

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Innovative Research Mouse Plasma used in University of Pittsburgh Study

Posted by Wendy Wise on

Innovative Research Mouse Plasma used in University of Pittsburgh Study

Researchers at the University of Pittsburgh published a study in the Journal of Immunology and Regenerative Medicine using mouse plasma from Innovative Research. Innovative Research offers a wide range of mouse plasma types, including genetically deficient and depleted plasmas, in addition to US Origin CD1, Balb C, C57BL/6 and others.The study examines three types of extracellular vesicles present in bone, blood and extracellular matrix. The results inform metrics for the categorization of EV and provide tools for the isolation of EV for potential diagnostic and therapeutic applications. Extracellular vesicles present in bone, blood and extracellular matrix have distinctive characteristics and...

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Nanog protein reverses signs of aging in new study in Science Advances from scientists at the University at Buffalo

Posted by Wendy Wise on

Nanog protein reverses signs of aging in new study in Science Advances from scientists at the University at Buffalo

Scientists from the University of New York at Buffalo published a study in Science Advances that supports that overexpression of the transcription factor NANOG can reverse the signs of cellular aging in muscles without having to revert the cells to a stem-cell like state. The work could help lead to new treatments or therapies that help reverse cellular senescence, and aid the many people suffering from age-related disorders. Read the study in Science Advances.  Ameliorating the hallmarks of cellular senescence in skeletal muscle myogenic progenitors in vitro and in vivo Aref Shahini, Nika Rajabian, Debanik Choudhury, Shahryar Shahini, Kalyan Vydiam, Thy...

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