Product References — Proteins

Use of Cyclodextrin as a Novel Agent in the SEC-HPLC Mobile Phase to Mitigate the Interactions of Proteins or Peptide or their Impurities with the Residual Silanols of Commercial SEC-HPLC Columns with Improved Separation and Resolution

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Rat IgG (Fractionated Purified) from Innovative Research was recently used in the following study: Use of Cyclodextrin as a Novel Agent in the SEC-HPLC Mobile Phase to Mitigate the Interactions of Proteins or Peptide or their Impurities with the Residual Silanols of Commercial SEC-HPLC Columns with Improved Separation and ResolutionJaveri, I., Nellaiappan, K., McNemar, C. et al. Pharmaceutical Research: September 2018, 35:168 "... Purified rat polyclonal IgG formulated in PBS at pH 7.4 was purchased from Innovative Research Novi, MI 48377... Rat IgG powder was diluted to 1 mg/mL using PBS before injection. All monoclonal antibodies formulated in product specific...

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Generating a canine anti-cancer IgE against the epidermal growth factor receptor (EGFR)

Posted by Leanne Kodsman on

Canine IgG Protein A Purified from Innovative Research was recently used in the following study: Generating a canine anti-cancer IgE against the epidermal growth factor receptor (EGFR) Judit Fazekas-Singer, MSc, Josef Singer, MD, PhD, Kristina M. Ilieva, MSc, Miroslawa Matz, MSc, Ina Herrmann, DVM, Edzard Spillner, PhD, Sophia N. Karagiannis, PhD, Erika Jensen-Jarolim, MD AllergoOncology, April 2018 ... used as human IgE isotype control was provided by Dr S.N. Karagiannis and Prof H.J. Gould, King's College London (London, UK). Purified canine IgG (cat IR-DG-GF, Innovative Research, Novi, MI, USA) was employed as canine IgG isotype control and purified canine IgE...

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Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection

Posted by Leanne Kodsman on

Human C-Reactive Protein (CRP) from Innovative Research was recently used in the following study: Small molecule detection with aptamer based lateral flow assays: Applying aptamer-C-reactive protein cross-recognition for ampicillin detection Lars Kaiser, Julia Weisser, Matthias Kohl & Hans-Peter Deigner Scientific Reports, Published 04 April 2018 ... We here report the cross-recognition of CRP and ampicillin by CRP and ampicillin aptamers, identified by in silico analysis of sequence homologies of both aptamers... C-reactive protein (CRP) was purchased from Innovative Research (Novi, MI) ...   Related products available from Innovative Research also include: Rabbit C-Reactive Protein (CRP) Rat C-Reactive Protein (CRP) Rhesus...

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Carboxypeptidase B2 and N play different roles in regulation of activated complements C3a and C5a in mouse

Posted by Leanne Kodsman on

Innovative Research's Fibrinogen products were recently used in the following study: Carboxypeptidase B2 and N play different roles in regulation of activated complements C3a and C5a in mouse J. Morser, Z. Shao, T. Nishimura, Q. Zhou, L Zhao, J. Higgins, L.L.K. Leung Journal of Thrombosis and Haemostasis, 31 January 2018 ... In some experiments, plasma was prepared and levels of C3, C5 and C5b-9 (LifeSpan Biosciences Inc., Seattle, WA), fibrinogen (Innovative Research, Novi, MI), D-dimer and thrombin-antithrombin complexes (TAT) determined by enzyme ...

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Evaluation of fluorescence-guided surgery agents in a murine model of soft tissue fibrosarcoma

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Innovative Research's non-specific Human IgG antibody was recently used in the following study: Evaluation of fluorescence-guided surgery agents in a murine model of soft tissue fibrosarcoma Andrew C. Prince BSc, Andrew S. McGee BA, Herrick Siegel MD, Eben L. Rosenthal MD, Nicole K. Behnke MD, Jason M. Warram PhD - Journal of Surgical Oncology, 2017 … Cetuximab is a chimeric, monoclonal anti-EGFR antibody. DC101 is a monoclonal anti-mouse VEGFR2 antibody. Lastly, a non-specific Human IgG antibody (Cat: IR-Hu-GF-7312TG; Innovative Research, Peary Court Novi, MI) was employed as a control …

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