Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L

Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L

Posted by Leanne Kodsmann on

IgG isotype control from Innovative Research was used in the following study:

 

Cellular proliferation in mouse and human pancreatic islets is regulated by serpin B13 inhibition and downstream targeting of E-cadherin by cathepsin L

Chi-Wen Lo, Yury Kryvalap, Tzong-jen Sheu, Ching-Ho Chang, Jan Czyzyk

Diabetologia
May 2019, Volume 62, Issue 5, pp 822–834

"... We used an in vitro culture system consisting of isolated pancreatic islets, an extract of pancreatic ductal epithelium and a monoclonal antibody (mAb) to serpin B13 or IgG isotype control. ... IgG isotype control (Innovative Research, Novi, MI, USA) were added to the islet cultures (4 μg/ml each). Antibodies were stored and diluted in phosphate buffered saline (PBS). B29 was validated by western blotting (ESM Fig. 1). ..."

 

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  • Tags: Antibodies, Proteins

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