Posted by Corey Marcath on
tPA from Innovative Research was used in the following study:
Structures of full-length plasma kallikrein bound to highly specific inhibitors describe a new mode of targeted inhibition
James R. Partridge, Rebea M. Choy, Abel Silva-Garcia, Chul Yu, Zhe Li, Hing Sham, Brian Metcalf
Journal of Structural Biology
1 March 2019
"...Plasma kallikrein (pKal) is a serine protease responsible for cleaving high molecular-weight kininogen to produce the pro-inflammatory peptide, bradykinin. Unregulated pKal activity can lead to hereditary angioedema (HAE) following excess bradykinin release.tPA from Innovative Research (Novi MI)..."
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