Product References — Animal Plasma

Red Blood Cells and Lipoproteins: Important Reservoirs and Transporters of Polyphenols and Their Metabolites

Posted by Adam Awdish on

Red Blood Cells and Lipoproteins: Important Reservoirs and Transporters of Polyphenols and Their Metabolites

Innovative Grade US Origin Porcine Plasma from Innovative Research was used in the following study:   Red Blood Cells and Lipoproteins: Important Reservoirs and Transporters of Polyphenols and Their Metabolites Salwa M. Harbi, Rania A. Hussien, Intesar Hawasawi, Ibtehaj Alshdoukhi, Vikram Chopra, Amal N. Alanazi, William Butler, Rakia Koroma, Colin Peters, Deanne D. Garver, and Joe A. Vinson Journal of Agricultural and Food Chemistry June 4, 2020 Dietary polyphenols are protective agents in the body against chronic diseases. Polyphenols bind to proteins and cells in blood including RBC, albumin and lipoproteins described in this study. This potentially benefits both proteins and RBC...

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Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics

Posted by Corey Marcath on

Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics

Innovative Grade US Origin Canine Beagle Plasma from Innovative Research was used in the following study:   Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E.Haefeli Journal of Pharmaceutical and Biomedical Analysis 27 March 2020 Bremelanotide (Vyleesi®) is an -melanocyte-stimulating hormone analog that was recently approved for the treatment of premenopausal hypoactive sexual desire disorder (HSDD; [1]). It is a cyclic heptapeptide (sequence: Ac-Nle-cyclo[Asp-His-d-PheArg-Trp-Lys]−OH) that is cyclized via amide bonding of the side chain carboxy-function of Asp to the amino group of the side...

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Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment

Posted by Corey Marcath on

Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment

Innovative Grade US Origin Rat Wistar Plasma from Innovative Research was used in the following study:   Carvacrol loaded nanostructured lipid carriers as a promising parenteral formulation for leishmaniasis treatment Juliana G. Galvãoa, Raquel L. Santosa, Audrey R.S.T. Silvab, Jeferson S. Santosa, Amanda M.B. Costaa , Hardik Chandasanac, Valter V. Andrade-Netod, Eduardo Caio Torres-Santosd, Ana Amélia M. Liraa, Silvio Dolabellab, Ricardo Scherb, Peter E. Kimae, Hartmut Derendorfc, Rogéria S. Nunes European Journal of Pharmaceutical Sciences 1 July 2020 “Leishmaniasis are a group of neglected infectious diseases caused by protozoa of the genus Leishmania with distinct presentations. The available leishmaniasis treatment...

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Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma

Posted by Corey Marcath on

Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma

Single Donor Human Plasma (Blood Derived) and Innovative Grade US Origin Rat Sprague Dawley Single Donor Plasma from Innovative Research was used in the following study:   Statistical optimization and validation of a novel ultra-performance liquid chromatography method for estimation of nintedanib in rat and human plasma Snehal K Shukla, Hossam Kadry, Jayshil A Bhatt, Rasha Elbatanony, Fakhrul Ahsan & Vivek Gupta Future Science 13 Feb 2020 “A high throughput ultra-performance liquid chromatography (UPLC)-ultraviolet method for quantification of nintedanib in rat and human plasma was developed and optimized using chemometrical approach… Rat plasma and human plasma were acquired from Innovative...

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Combined maternal exposure to cypermethrin and stress affect embryonic brain and placental outcomes in mice

Posted by Corey Marcath on

Combined maternal exposure to cypermethrin and stress affect embryonic brain and placental outcomes in mice

Innovative Grade US Origin Mouse CD1 Plasma from Innovative Research was used in the following study:   Combined maternal exposure to cypermethrin and stress affect embryonic brain and placental outcomes in mice Benjamin A. Elser, Khaled Kayali, Ram Dhakal, Bailey O’Hare, Kai Wang, Hans Joachim Lehmler, and Hanna E. Stevens Toxicological Sciences 19 March 2020 “Prenatal exposure to cypermethrin is a risk factor for adverse neurodevelopmental outcomes in children. In addition, maternal psychological stress during pregnancy has significant effects on fetal neurodevelopment and may influence end-stage toxicity to offspring by altering maternal xenobiotic metabolism…untreated mouse plasma (Innovative Research, Novi, MI,...

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