Product References — Animal Plasma

Innovative Grade US Origin Rat Sprague Dawley Whole Blood and Innovative Grade US Origin Rat Sprague Dawley Plasma from Innovative Research was used in the following study:   Sensitive and Rapid UHPLC–MS/MS Assay for Simultaneous Quantifications of Calcipotriol and Paclitaxel in Rat Whole Blood and Plasma Samples Victor R. Lincha, Cheng-Hui Hsiao, Jun Zhao, Chun Li, Diana S-L Chow Journal of Pharmaceutical and Biomedical Analysis October 9, 2020 The potential benefits of stroma-depleting agents combined with chemotherapy for pancreatic ductal adenocarcinoma (PDAC) treatment has been examined in vitro and in transplantation studies. Unfortunately, this type of treatment has failed in...

Innovative Grade US Origin Mouse C57BL6 Plasma from Innovative Research was used in the following study:   Poly (Ethylene Glycol)-Block-Poly (D, L-lactide) (PEG-PLA) Micelles for Brain Delivery of Baicalein through Nasal Route for Potential Treatment of Neurodegenerative Diseases due to Oxidative Stress and Inflammation: An in vitro and in vivo Study Li Zhang, Shili Yang, Lizhen Huang, Paul Chi-Lui Ho International Journal of Pharmaceutics October 15, 2020 Baicalein (BE) is a flavonoid isolated from Scutellaria radix roots. Previous studies have already demonstrated that BE has various pharmacological effects on the brain, including antioxidant and anti-inflammatory effects, that contribute to its...

Innovative Grade US Origin Canine Beagle Plasma from Innovative Research was used in the following study:   Post-Extraction Disulfide Bond Cleavage for MS/MS Quantification of Collision-Induced Dissociation-Resistant Cystine-Cyclized Peptides and its Application to the Ultra-Sensitive UPLC-MS/MS Bioanalysis of Octreotide in Plasma Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli Analytica Chimica Acta April 10, 2020 Peptides are gaining importance in therapeutics due to their biocompatibility and chemical diversity. However, linear peptides are prone to degradation. Cyclic peptides, in contrast, have significant advantages over linear peptides, especially if the peptides are small. Cyclic peptides are usually resistant to collision-induced dissociation...

Innovative Grade US Origin Monkey Cynomolgus Plasma and Innovative Grade US Origin Monkey Rhesus Plasma from Innovative Research was used in the following study:   Anti-Coagulation Factor XI Antibodies Zhu Chen, Kenneth Ellsworth, James Milligan, Elizabeth Oldham, Dietmar Seiffert, Vaishnavi Ganti, Mohammad Tabrizifard, Bianka Prinz US Patent Pending August 13, 2020 Thromboembolic disorders are one of the leading causes of death in the Western world despite the availability of numerous types of anticoagulants, like vitamin K antagonists (VKAs), heparins, and direct thrombin inhibitors. Though these drugs are effective in reducing thrombosis, they also come with some serious side effects. VKAs,...

Mouse Non-Swiss Albino Plasma and Pooled Human Plasma Apheresis Derived from Innovative Research were used in the following study:   Metabolism of a Kratom Alkaloid Metabolite in Human Plasma Increases Its Opioid Potency and Efficacy Shyam H. Kamble, Francisco León, Tamara I. King, Erin C. Berthold, Carolina Lopera-Londoño, Kanumuri Siva Rama Raju, Aidan J. Hampson, Abhisheak Sharma, Bonnie A. Avery, Lance R. McMahon, and Christopher R. McCurdy ACS Pharmacology & Translational Science July 31, 2020 Kratom is commonly used in the United States for self-treatment of pain and opioid withdrawal symptoms. Mitragynine is the most abundant alkaloid in kratom, and...