Select this product for Molecular Innovations name, GC Globulin, Human Plasma, Mixed Type and product number, HGCG.Human Vitamin D-binding protein Purified Lyophilized from Innovative Research has been purified from human plasma. This product is offered in a lyophilized powder format, buffered in 0.02M Sodium Phosphate; 0.15M NaCl; pH 7.4, with a purity of >95% by SDS-PAGE analysis.GC globulin, also known as Vitamin D-binding protein (DBP/VDB), Vitamin D-binding protein-macrophage activating factor (DBP-MAF), and Gc protein-derived macrophage activating factor (Gc-MAF), is an alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100 ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin with high affinity. GC-globulin also binds membranes of both circulating B and T lymphocytes. Clinically, concentrations are reduced in patients with severe liver diseases. GC-globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.More Details: Source: Human plasma Purity: >95% by SDS-PAGE analysis Storage Conditions: -70 C At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.For research use only.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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