Select this product for Molecular Innovations name, Human Thrombin Activatable Fibrinolysis Inhibitor and product number, TAFI.

Human Thrombin Activatable Fibrinolysis Inhibitor (TAFI) from Innovative Research, also known as plasma procarboxypeptidase-B and carboxypeptidase-U, is a single chain glycoprotein that is cleaved by thrombin, plasmin and trypsin. TAFI is purified from normal human plasma using immunoaffinity and ion-exchange chromatography. Activated TAFI cleaves C-terminal lysines on fibrin and cell surfaces resulting in down-regulation of fibrinolysis by reducing the number of plasminogen and tPA binding sites on fibrin.

More Details:

• Species: Human
• Purity: >95% by SDS-PAGE analysis
• Source: Human plasma
• Buffer: 0.02M Hepes; 0.2M NaCl; pH 7.4
• Storage Conditions: - 70 C

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For research use only.

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This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.

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