News

(February 2, 2015) Innovative Research's Human Cortisone Chemiluminescent CLIA Kit was recently used in the following study:

Inhibition of 11-HSD2 expression by triclosan via induction of apoptosis in human placental syncytiotrophoblasts

N Zhang, W Wang, W Li, C Liu, Y Chen, Q Yang - The Journal of Clinical , 2015
Cortisol and cortisone levels were then measured with enzyme immuno- assay (EIA) kits (Human Cortisol Immunoassay kit, R&D Sys- tems, Minneapolis, MN and Human Cortisone Chemiluminescent CLIA Kit, Innovative Research, Novi, MI, respectively...

(January 6, 2015) Innovative Research's Human Neutrophil Elastase was recently used in the following study:

Synthesis and biological evaluation of nigranoic acid esters as novel human neutrophil elastase inhibitors

G Huang, L Feng, B Liu, Y He, Y Li, Y Chen - Natural Product Research, 2015
HNE activity inhibitory bioassay. HNE (EC 3.4.21.37) from human leucocytes was purchased from Innovative Research Company (Novi, Michigan). ONO-5046,HNE substrate (MeOSucAlaAlaProValpNA), soybean...

(December 5, 2014) Innovative Research's Single Donor Human Whole Blood was recently used in the following study:

The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells

AE Turley, JW Zagorski, CE Rockwell - Cytokine, 2015
b Cellular and Molecular Biology Program, Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA. Received 7 February 2014, Revised 16 October 2014, Accepted 6 ... Whole human blood was purchased from Innovative Research (Novi, MI).

While monoclonal antibodies are widely used for therapeutically and commercially, recent developments show that bispecific antibodies (bsAbs), or dual specificity antibodies, may be more successful as they are able to focus on two or more targets.

bsAbs can redirect immune effector cells to enhance tumor destruction. According to the GEN News article, "by targeting two different receptors in combination on the same cell, these antibodies can induce modifications of cell signaling, including the inactivation of proliferation or inflammatory pathways."

(October 3, 2014) Innovative Research Innovative Grade US Origin Bovine Whole Blood was recently used in the following study:

Direct Mass Spectrometry Analysis of Biofluid Samples Using SlugFlow Microextraction NanoElectrospray Ionization

Y Ren, MN McLuckey, J Liu, Z Ouyang - Angewandte Chemie, 2014
All the experiments were carried out with a TSQ Quantum Access Max mass spectrometer (Thermo Fisher Scientific, San Jose, CA, USA). The bovine blood was purchased from Innovative Research Inv. (Novi, MI, USA).