Case closed? Genetic testing provides insight into unexplained sudden deaths of Amish children
A series of sudden and unexplained deaths among seemingly healthy Amish children has been a mystery for years. New technology...
PAI-1 Mutation in Amish Community Could Lead to New Treatments for Age-Related Disorders
A genetic mutation in SERPINE1, the gene responsible for Plasminogen Activator Inhibitor-1 (PAI-1), seems to have ties back to leading...
The case for PAI-1 as a biomarker for major depressive disorder and antidepressant resistance
New research validates the PAI-1 knockout mouse as a preclinical genetic model of human depression, while demonstrating that this knockout...
