Urinary Plasmin(ogen) as a Prognostic Factor for Hypertension

Posted by Leanne Kodsman on

Human Plasminogen Total ELISA Kit from Innovative Research was recently used in the following study:

Urinary Plasmin(ogen) as a Prognostic Factor for Hypertension

Evan C. Ray, MD, PhD, Rachel G. Miller, PhD, John E. Demko, MD, Tina Costacou, PhD, Carol L. Kinlough, PhD, Casey L. Demko, MS, Mark L. Unruh, MD, Trevor J. Orchard, MD, Thomas R. Kleyman, MD
Kidney International Reports (2018)

"... For urinary plasmin(ogen) measurement in the present study, archived specimens stored at -80 ËšC were thawed on ice and centrifuged at 10,000 g for 15 minutes at 4 ËšC to remove particulate matter. Specimens were then diluted 10 to 100-fold before plasmin(ogen) measurement via ELISA (Innovative Research, Novi, MI). Although this method does not distinguish active plasmin from plasminogen, results using this assay correlate well with urine plasmin as measured by immunoblot."

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