Hericium erinaceus isolectins recognize mucin-type O-glycans as tumor-associated carbohydrate antigens on the surface of K562 human leukemia cells

Posted by Leanne Kodsman on

Porcine Red Blood Cells Packed 10% from Innovative Research was recently used in the following study:

Hericium erinaceus isolectins recognize mucin-type O-glycans as tumor-associated carbohydrate antigens on the surface of K562 human leukemia cells

Seonghun Kim
Biological Macromolecules, August 2018

" ... Animal blood products and glycoconjugates [Galβ(1,3)GalNAc; Neu5Acα(2,3)Galβ(1,3)GalNAc; Galβ(1,6)GalNAc] were purchased from Innovative Research (Novi, MI, USA) and ... The hemagglutination activity of lectins was determined using the following twofold serial dilution procedure with intact erythrocytes. Lectin-containing solution (50 μL) was mixed with an equal volume of 4% (v/v) formaldehyde-treated porcine red blood cells suspended in PBS in individual wells of a 96-well microtiter plate ... "

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