Tranexamic Acid Analysis as Ethoxycarbonyl-tert-butyldimethylsilyl Derivatives by Gas Chromatography–Tandem Mass Spectrometry

Tranexamic Acid Analysis as Ethoxycarbonyl-tert-butyldimethylsilyl Derivatives by Gas Chromatography–Tandem Mass Spectrometry

Innovative Grade US Origin Mouse Balb C Serum from Innovative Research was used in the following study:

 

Tranexamic Acid Analysis as Ethoxycarbonyl-tert-butyldimethylsilyl Derivatives by Gas Chromatography–Tandem Mass Spectrometry

Hyung-Jin Park, Hyeon-Seong Lee, Chan Seo, Jeuk Min, Moongi Ji, Youngbae Kim, Subin Choi, Doo-Young Kim, Jung Dong Kim, Do Hyeon Jeong, Wonjae Lee, and ManJeong Paik

KOREAN CHEMICAL SOCIETY KOREAN CHEMICAL SOCIETY
January 5, 2020

“…Tranexamic acid (TA, Figure 1) as a synthetic derivative of lysine is known as potent antifibrinolytic drug.1–4 TA interacts at the lysine-binding site of plasminogen molecules during fibrinolysis, which inhibit plasminogen activators from converting plasminogen to plasmin… Mouse balb/C serum was purchased from Innovative Research (Novi, MI, USA)…” 

 

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