Posted by Adam Awdish on
Single Donor Human Whole Blood from Innovative Research was used in the following study:
Ashlee J. Colbert, Katrina Co, Giselle Lima-Cooper, Dong Hoon Lee, Katherine N. Clayton, Steven T. Wereley, Chandy C. John, Jacqueline C. Linnes, and Tamara L. Kinzer-Ursem
March 22, 2021
There are over 200 million global cases and over 400,000 deaths resulting from malaria each year. Currently, rapid diagnostic tests are not sensitive or specialized enough to detect low concentrations of parasites in patients that are not displaying symptoms. In this study, researchers investigated the potential of using smartphones for rapid diagnosis of malaria. Researchers combined an imaging-based sensing technique called particle diffusometry (PD) with loop mediated isothermal amplification (LAMP) on a smartphone. After amplifying a sample treated with a fluorescent solution, a 30-second video was recorded on the smartphone and the nanoparticle movement was observed. The researchers were able to detect as few as one parasite per microliter of blood within 45 minutes without DNA extraction.
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