Towards the Use of a Smartphone Imaging-Based Tool for Point-of-Care Detection of Asymptomatic Low-Density Malaria Parasitemia

Towards the Use of a Smartphone Imaging-Based Tool for Point-of-Care Detection of Asymptomatic Low-Density Malaria Parasitemia

Posted by Adam Awdish on

Single Donor Human Whole Blood from Innovative Research was used in the following study:

 

Towards the Use of a Smartphone Imaging-Based Tool for Point-of-Care Detection of Asymptomatic Low-Density Malaria Parasitemia

Ashlee J. Colbert, Katrina Co, Giselle Lima-Cooper, Dong Hoon Lee, Katherine N. Clayton, Steven T. Wereley, Chandy C. John, Jacqueline C. Linnes, and Tamara L. Kinzer-Ursem

Malaria Journal
March 22, 2021

There are over 200 million global cases and over 400,000 deaths resulting from malaria each year. Currently, rapid diagnostic tests are not sensitive or specialized enough to detect low concentrations of parasites in patients that are not displaying symptoms. In this study, researchers investigated the potential of using smartphones for rapid diagnosis of malaria. Researchers combined an imaging-based sensing technique called particle diffusometry (PD) with loop mediated isothermal amplification (LAMP) on a smartphone. After amplifying a sample treated with a fluorescent solution, a 30-second video was recorded on the smartphone and the nanoparticle movement was observed. The researchers were able to detect as few as one parasite per microliter of blood within 45 minutes without DNA extraction.

 

Related products available from Innovative Research also include:

Single Donor Human Red Blood Cells

Pooled Human Complement Serum

Single Donor Human Platelets ACD

  • Tags: Human Blood Cells, Human Whole Blood, Single Donor Human Whole Blood 

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