Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers

Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers

Single Donor Human Red Blood Cells from Innovative Research was used in the following study:

 

Synthesis of Lysine Mimicking Membrane Active Antimicrobial Polymers

Ankita Arora, Wan Zheng, Hongjun Liang, Abhijit Mishra

Advances in Polymer Sciences and Technology
Materials Horizons: From Nature to Nanomaterials (2018).

"... In this study, we synthesize lysine mimicking homopolymer and lysine mimicking copolymer with hydrophobic group and study their antimicrobial activity against both Gram-positive and Gram-negative bacteria. The advantage of using such antibiotic polymers over conventional AMPs is their scalability, cost-effectiveness and chemical stability in in vivo environment ... Fresh human red blood cell (HRBC) is purchased from Innovative Research Inc. (Novi, MI), stored at 4 °C and used within 2 weeks ..."

 

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