Suppression of Wild-Type Amplification by Selectivity-Enhancing Agents in PCR Assays That Utilize SuperSelective Primers for the Detection of Rare Somatic Mutations

Normal Single Donor Human Plasma from Innovative Research was recently used in the following study:

Suppression of Wild-Type Amplification by Selectivity-Enhancing Agents in PCR Assays That Utilize SuperSelective Primers for the Detection of Rare Somatic Mutations

Diana Y.Vargas, Salvatore A.E. Marras, SanjayTyagi, Fred R.Kramer
The Journal of Molecular Diagnostics, April 2018

... Digested KRAS G12A mutant plasmid DNA was spiked into normal single-donor human plasma (IPLA-N-S; Innovative Research, Novi, MI). The plasma was first centrifuged at 5000 rpm for 5 minutes ...

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