Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile

Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile

Posted by Adam Awdish on

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:

 

Soluble Sema4D in Plasma of Head and Neck Squamous Cell Carcinoma Patients is Associated with Underlying Non-Inflamed Tumor Profile

Rania H. Younis, Ioana Ghita, Manar Elnaggar, Risa Chaisuparat, Vasileios Ionas Theofilou, Donita Dyalram, Robert A. Ord, Eduardo Davila, Luke J. Tallon, John C. Papadimitriou, Tonya J. Webb, Søren M. Bentzen, and Joshua E. Lubek

Frontiers in Immunology
March 11, 2021

Semaphorin 4D (Sema4D) is a glycoprotein that is capable of functioning as both a membrane bound protein or as a cleaved soluble protein (sSema4D), and it is expressed by several different tumors and types of immune cells. Researchers in this study aimed to investigate the potential of plasma sSema4D as an immune marker in patients with head and neck squamous cell carcinoma (HNSCC). They observed significant changes in gene expression and inflammatory responses, however these associations could not be readily explained. The researchers did conclude, however, that there is a link between sSema4D and a patient’s histological inflammatory subtype.

 

Related products available from Innovative Research also include:

Single Donor Human Serum Off The Clot

Pooled Human Plasma (Blood Derived)

Pooled Human Plasma Apheresis Derived

  • Tags: Human Plasma, Single Donor Human Plasma Whole Blood Derived

    • The next big thing: it's what you do. The biological research materials you need to discover it? That's what we do! We love seeing how our products are being used in real-life applications and contributing to scientific acheivements every day. With thousands of published references and decades of proven results, you can count on us to help you source the high-quality biomaterials you need that will deliver reliable, consistent results - kit to kit, lot to lot, all study long. So what are you waiting for? All great discoveries start somewhere... yours starts with Innovative Research! Get in touch with our team today!


    Related Posts

    We Have Biological Products and Research Materials to Assist Forensic Investigations
      Forensic crime labs use a variety of biological materials and techniques to analyze e...
    Read the Article
    Plasma MMP-3: A Novel Biomarker Predicting ARDS Patient Outcomes
    In the quest to enhance patient care in critical conditions, the discovery of predictiv...
    Read the Article
    Top 5 Biologicals to Buy Right Now
    Innovative Research is excited to share our top 5 biological products that are making w...
    Read the Article

    ← Older Post Newer Post →

    ×