Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry

Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry

Single Donor Human Whole Blood from Innovative Research was used in the following study:

 

Simultaneous determination of cardiovascular drugs in dried blood spot by liquid chromatography-tandem mass spectrometry

Hyung MinKim, Ju-Hwan Park, Nguyen Phuoc Long, Dae-Duk Kim, Sung Won Kwon

Journal of Food and Drug Analysis
October 2019

“…A dried blood spot (DBS) sampling method was exploited to extract cardiovascular drugs using a small volume of whole blood of human and rodent. Thereafter, an analytical method using liquid chromatography with tandem mass spectrometry (LC-MS/MS) was developed and validated for the determination of 12 cardiovascular drugs. …Human whole blood with EDTA was purchased from Innovative Research (Novi, MI, USA), which is a supplier of human blood samples…”

 

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