Nicole E. Behrens, Peter N. Lipke, Darrell Pilling, Richard H. Gomer, Stephen A. Klotz
Host-Microbe Biology
12 March 2019
"In patients with invasive fungal diseases, there is often little cellular inflammatory response. We tested the idea that binding of the human constitutive plasma protein serum amyloid P component (SAP) (also called PTX2) to Candida albicans dampens the innate immune response to this fungus...For other experiments, alongside the addition of C. albicans alone to wells or chambers, C. albicans was also incubated in 100% normal human male AB serum (Innovative Research, Novi, MI)..."
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