Posted by Leanne Kodsman on
Experimental and Therapeutic Medicine, August 2018
... PAI-1 and TGF-beta levels in BAL fluids were measured at 0, 4, 12, 18, and 24 weeks after irradiation using ELISA kits for PAI-1 (Innovative Research, Novi, MI, USA)... To determine the effect of thoracic irradiation on the expression of PAI-1 and TGF-beta in the lung, PAI-1 and TGF-beta levels in BAL fluid were measured using ELISA kits. In WT mice, PAI-1 levels in BAL fluids were unchanged from baseline until 12 weeks after irradiation but started increasing after 18 weeks and reached their highest levels at 24 weeks after irradiation..."
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