Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinctfrom Astrocytopathy Induced by AQP4-IgG

Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinctfrom Astrocytopathy Induced by AQP4-IgG

Posted by Corey Marcath on

Pooled Human Complement Serum from Innovative Research was used in the following study:

 

Myelin Oligodendrocyte Glycoprotein-IgG Contributes to Oligodendrocytopathy in the Presence of Complement, Distinctfrom Astrocytopathy Induced by AQP4-IgG

Ling Fang, Xinmei Kang, Zhen Wang, Shisi Wang, Jingqi Wang, Yifan Zhou, Chen Chen, Xiaobo Sun, Yaping Yan, Allan G. KermodeLisheng Peng, Wei Qiu

Neuroscience Bulletin
18 January 2019

“...Immunoglobulin G against myelin oligodendrocyte glycoprotein (MOG-IgG) is detectable in neuromyelitis optica spectrum disorder (NMOSD) without aquaporin4 IgG (AQP4-IgG), but its pathogenicity remains unclear. In this study, we explored the pathogenic mechanisms of MOG-IgG in vitro and in vivo and compared them with those of AQP4-IgG. …Human complement (hC) from Innovative Research (IPLA-CSER, Innovative Research, Novi, MI) was stored at - 80 C…”

 

Related products available from Innovative Research also include:

Pooled Human Complement Serum

Single Donor Human Plasma (Blood Derived)

Single Donor Human Whole Blood

Pooled Human Plasma Apheresis Derived

  • Tags: Human Serum, pooled human complement plasma

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