Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls

Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls

Posted by Corey Marcath on

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:

 

Mathematical model of thrombin generation and bleeding phenotype in Amish carriers of Factor IX:C deficiency vs. controls

S. Guptaa, M.C. Bravob, M. Heimana, C. Nakara, K. Brummel-Ziedinsb , C.H. Millerc, A. Shapiro

Thrombosis Research
08 August 2019

“…Hemophilia B (HB) is an X-linked bleeding disorder resulting in a deficiency of FIX:C. Variable FIX:C levels can be seen in carriers within the same pedigree with a unifying mutation …therefore to ensure that other inheritable factors which could potentially impact coagulation did not affect the TG results, we also included 15 samples of fresh frozen plasma from healthy female non Amish controls (NAC; age = 33 ± 9, range 21–51) purchased from Innovative Research (Novi, MI)...”

 

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  • Tags: Human Plasma, Single Donor Human Plasma Whole Blood Derived

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