In vitro study of new combinations for local antibiotic therapy with calcium sulphate – Near constant release of ceftriaxone offers new treatment options

In vitro study of new combinations for local antibiotic therapy with calcium sulphate – Near constant release of ceftriaxone offers new treatment options

Posted by Leanne Kodsmann on

Innovative Grade US Origin Bovine Plasma from Innovative Research was used in the following study:

 

In vitro study of new combinations for local antibiotic therapy with calcium sulphate – Near constant release of ceftriaxone offers new treatment options

Peter Wahl, Karolin Rönn, Marc Bohner, Laurent A Decosterd, Christoph Meier, Michel Schläppi, Sandrine Festa, Emanuel Gautier

Journal of Bone and Joint Infection, October 2018

"... For every antibiotic, 5 g of pellets were placed in each of four closed glass tubes. The elution experiment was run in triplicate, while the fourth tube allowed sampling of whole pellets for agar diffusion tests. Each tube was filled with 10 ml of elution fluid, exchanged daily by pouring it out and refilling. As the aim of the experiment was to assess stability and activity of the antibiotics over a prolonged period of time, no thorough rinsing of the pellets was performed in order to avoid accidental losses of material and drug washout. The experiment was run once with isotonic phosphate-buffered saline ... and then repeated with bovine plasma (IBV-K2 EDTA, lot 11035, Innovative Research, Novi, MI, USA) for those antibiotics that showed prolonged stability in the first phase ..."

 

Related products available from Innovative Research also include:

  • Tags: Animal Plasma, Innovative Grade US Origin Bovine Plasma, Journal: Journal of Bone and Joint Infection

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