Enhancing Treatment Efficacy of 177Lu-PSMA-617 with the Conjugation of an Albumin-Binding Motif: Preclinical Dosimetry and Endoradiotherapy Studies

Posted by Leanne Kodsman on

Human Serum from Innovative Research was recently used in the following study:

Enhancing Treatment Efficacy of 177Lu-PSMA-617 with the Conjugation of an Albumin-Binding Motif: Preclinical Dosimetry and Endoradiotherapy Studies

Hsiou-Ting Kuo, Helen Merkens, Zhengxing Zhang, Carlos F. Uribe, Joseph Lau, Chengcheng Zhang , Nadine Colpo , Kuo-Shyan Lin , and François Bénard
Molecular Pharmaceutics, September 2018

"... All chemicals and solvents were obtained from commercial sources, and used without further purification. Human serum for protein binding assay was obtained from Innovative Research (Novi, MI)... Plasma protein binding assays were performed according to literature methods Briefly, 37 kBq of 177Lu-PSMA-617 or 177Lu-HTK01169 in 50 µL PBS was added into 200 µL human serum and the mixture was incubated at room temperature for 1 min..."

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