Effect of difluoroacetic acid and biological matrices on the development of a liquid chromatography–triple quadrupole mass spectrometry method for determination of intact growth factor proteins
Posted by Corey Marcath on
Pooled Human Urine and Pooled Human Serum Off The Clot from Innovative Research was used in the following study:
Alex J. Rai Kevin A. Schug, Katarína Maráková
Journal of Separation Science
2/7/2020
“In biological systems, variable protein expression is a crucial marker for numerous diseases, including cancer. The vast majority of liquid chromatography–triple quadrupole mass spectrometry-based quantitative protein assays use bottom-up methodologies, where proteins are subjected to proteolytic cleavage prior to analysis. …As biological matrices, pooled human urine and pooled human serum were purchased from Innovative Research (Novi, MI, USA)...”
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