Durable targeting of B-lymphocytes in living mice

Posted by Leanne Kodsman on

Sheep Red Blood Cells from Innovative Research were recently used in the following study:

Durable targeting of B-lymphocytes in living mice

M. Cascalho, D. Huynh, A. R. Lefferts, L. Stein, T. Lanigan, J. Decker, L. D. Shea & J. L. Platt
Scientific Reports (2018)

"... Transduction of CD19+ Cells in vivo: One hundred microliters of concentrated lentiviruses (3xMOI) were injected directly into the spleen (visualized and mobilized through laparotomy) in mice that had been immunized i.p. with 2.5 x 10^8 sheep red blood cells (Innovative Research, Novi, MI) 3 days before ..."

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