Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

Posted by Corey Marcath on

Innovative Grade US Origin Sheep Whole Blood Defibrinated from Innovative Research was used in the following study:

 

Dual Carbon Dioxide Capture to Achieve Highly Efficient Ultra-Low Blood Flow Extracorporeal Carbon Dioxide Removal

BRIAN Y. CHANG and STEVEN P. KELLER

Biomedical Engineering Society
2/1/2020

“Extracorporeal CO2 removal is a highly promising support therapy for patients with hypercapnic respiratory failure but whose clinical implementation and patient benefit is hampered by high cost and highly specialized expertise required for safe use. Current approaches target removal of the gaseous CO2 dissolved in blood which limits their ease of clinical use as high blood flow rates are required to achieve physiologically significant CO2 clearance… To simplify evaluation of transport kinetics, nonionic species and potassium were ignored so that the dialysate was only composed of sodium and chloride ions. Defibrinated ovine blood (Innovative Research, Novi, MI) and dialysate flows were perfused via roller pump through the previously described circuit in a single-pass one-way configuration…”

 

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  • Tags: Animal Whole Blood, Innovative Grade US Origin Sheep Whole Blood Defibrinated

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