Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Posted by Corey Marcath on

Single Donor Human Plasma (Blood Derived) from Innovative Research was used in the following study:

 

Determination of tafenoquine in human plasma by dispersive liquid‐liquid microextraction

Amanda M. G. Lobo Igor R. S. Magalhães

SSC plus
12/12/2019

“Tafenoquine, a synthetic analogue of primaquine, is a promising agent for the treatment of human malaria since this drug shows better antimalarial activity than primaquine in vitro and short treatment course. There are some methods for the quantification of tafenoquine in plasma, but none uses dispersive-liquid-liquid microextraction, an extraction technique that shows some advantages, such as miniaturization, low cost and high potential for routine application… The study was conducted using only normal single donor plasma specimens, which are commercially sold for in vitro use only (Innovative Research, Novi, MI, USA). These samples were stored frozen at −20◦C and, prior to use, were allowed to thaw at room temperature. Plasma quality control samples (QC)…”

 

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  • Tags: Human Plasma, Single Donor Human Plasma Whole Blood Derived

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