Posted by Leanne Kodsmann on
CD-1 Mouse Plasma from Innovative Research was used in the following study:
John R. Lever, Emily A.Fergason-Cantrell, Terry L. Carmack, Lisa D. Watkinson, Fabio Gallazzi
Nuclear Medicine and Biology
Volume 70, March 2019, Pages 53-66
"... Peripheral mu (μ) opioid receptors are implicated in pain, bowel dysfunction and the progression of certain cancers. In an effort to identify radioligands well suited for imaging these peripheral sites, we have prepared and evaluated four hydrophilic [111In]-labeled, DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) conjugated μ tetrapeptides. ... Heparinized CD-1 mouse plasma (Innovative Research, Novi, MI) was prepared for use by removing precipitates using centrifugation (2500 RPM, 5 min) at ambient temperature. Plasma aliquots were then spiked with [111In]-DOTA complex (300,000–500,000 CPM/mL), vortexed for 30 s, and incubated at 37 °C for 30 min. ..."
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