Use of Cyclodextrin as a Novel Agent in the SEC-HPLC Mobile Phase to Mitigate the Interactions of Proteins or Peptide or their Impurities with the Residual Silanols of Commercial SEC-HPLC Columns with Improved Separation and Resolution

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Rat IgG (Fractionated Purified) from Innovative Research was recently used in the following study:

Use of Cyclodextrin as a Novel Agent in the SEC-HPLC Mobile Phase to Mitigate the Interactions of Proteins or Peptide or their Impurities with the Residual Silanols of Commercial SEC-HPLC Columns with Improved Separation and Resolution

Javeri, I., Nellaiappan, K., McNemar, C. et al.
Pharmaceutical Research: September 2018, 35:168

"... Purified rat polyclonal IgG formulated in PBS at pH 7.4 was purchased from Innovative Research Novi, MI 48377... Rat IgG powder was diluted to 1 mg/mL using PBS before injection. All monoclonal antibodies formulated in product specific inactive excipients, which includes, buffer, salt, and or bulking agents such as Trehalose or Sucrose providing stability to the protein..."

Related products available from Innovative Research also include:

  • Tags: Proteins

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