Chromogenic Substrate for Plasmin Reference 2-11-15

Posted by Leanne Kodsman on

Innovative Research's Chromogenic Substrate For Plasmin was recently used in the following study:

Endogenous plasminogen activators mediate progressive intracranial hemorrhage after traumatic brain injury

N Hijazi, RA Fanne, R Abramovich, S Yarovoi, M Higazi… - Blood, 2015
WT-tPA (50 nM) or WT-uPA (5 nM) was incubated with plasminogen (500 nM) and the chromogenic substrate of plasmin S-2251 (Innovative Research, Inc. Novi, MI) (100 µM) alone or in the presence of tPA-S481A (100 nM) or tranexamic acid (1 µM).

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