Dean A. Rowe-Magnus, Adenine Y. Kao, Antonio Cembellin Prieto, Meng Pu, Cheng Kao
American Society for Microbiology 10 September 2019
”… All metazoans produce antimicrobial peptides (AMPs) that have both broad antimicrobial and immunomodulatory activity. Cathelicidins are AMPs that preferentially kill Gram-negative bacteria in vitro, purportedly by assembling into higher-order structures that perforate the membrane. We utilized high-resolution, single-cell fluorescence microscopy to examine their mechanism of action in real time. Human red blood cells (hRBCs) were purchased from Innovative Research, Inc. (Novi, MI)...”
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