Posted by Leanne Kodsmann on
Innovative Grade US Origin Rat Wistar Plasma from Innovative Research was used in the following study:
Ing-orn Prasanchaimontri, Hardik Chandasana, Mohammad A. Akbar, Steven Swarts, Paul Okuneiff, Hartmut Derendorf
European Journal of Pharmaceutics and Biopharmaceutics
Volume 135, February 2019, Pages 83-93
"... Fibroblast growth factor peptide (FGF-P) is a polypeptide analog of FGF-2 that could be a potential mitigation and treatment agent for radiation syndromes. Prior to conducting preclinical pharmacokinetics, we developed and validated the LC-MS/MS bioanalytical method for determination of FGF-P in rat plasma for the first time. FGF-P was extracted from rat plasma using the protein precipitation technique followed liquid-liquid extraction using dichloromethane as a solvent ... Drug-free Wistar rat plasma with sodium ethylenediaminetetraacetic acid (EDTA) was purchased from Innovative Research, Inc. (Novi, MI, USA) and stored at -20 ° C..."
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