Bioanalysis of ibrutinib and its dihydrodiol and glutathione cycle metabolites by liquid chromatography tandem mass spectrometry

Normal Single Donor Human Plasma from Innovative Research was recently used in the following study:

Bioanalysis of ibrutinib, and its dihydrodiol- and glutathione cycle metabolites by liquid chromatography-tandem mass spectrometry

J.J.M. Rooda, P.J.A. Dormans, M.J. van Haren, J.H.M. Schellens, J.H. Beijnen, R.W. Sparidans
Journal of Chromatography B, May 2018

... For the evaluation of selectivity and matrix effect, human lithium-heparinized plasma of six individual donors was obtained from Innovative Research (Novi, MI, USA). 2.2. Synthesis of small molecular thiol-conjugates ...

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